NYULangone at Chemotimelines 2024: Utilizing Open-Weights Large Language Models for Chemotherapy Event Extraction

AbstractThe extraction of chemotherapy treatment timelines from clinical narratives poses significant challenges due to the complexity of medical language and patient-specific treatment regimens. This paper describes the NYULangone team’s approach to Subtask 2 of the Chemotimelines 2024 shared task, focusing on leveraging a locally hosted Large Language Model (LLM), Mixtral 8x7B (Mistral AI, France), to interpret and extract relevant events from clinical notes without relying on domain-specific training data. Despite facing challenges due to the task’s complexity and the current capacity of open-source AI, our methodology highlights the future potential of local foundational LLMs in specialized domains like biomedical data processing.